JH Institute of Molecular Medicine

About the Institute:  Jamia Hamdard Institute of Molecular Medicine

JH-IMM aims to be a leading research Institute with expertise in and emphasis on biological, medical, chemical and computational approaches to biomedical research, particularly for investigating the molecular basis of human diseases and intervention.  Our vision is to articulate and lead in the evolving areas combining ‘traditional and modern medicine’, to be a major center of discovery in biomedical research and develop into a world-class science and educational research entity within the JH fraternity. The JH-IMM will also pursue a major educational mission providing state-of-the-art meetings and courses in biomedical research.

The mission of JH-IMM is to develop a multi-disciplinary approach via successful collaborations to bridge the gap between basic and clinical or translational sciences in India. This multidisciplinary interphase research is an unexplored area in our country, with vast unmet demands relevant to the health needs of the population.  Scientists at JH-IMM are involved in scientific programs, which try to integrate laboratory and clinical research, with an aim to develop new and innovative therapeutic modalities with an active interest in disease intervention strategies and assay development for diagnostic and therapeutic purposes. Interest will not be limited to vaccines or macro/micro-molecular clinical intervention but will also include traditional Indian medicines (Unani/Ayurvedic) along with marketed or phase III compounds to “repurpose or reposition” for various biological targets using proprietary assays and software.

Research Areas

The research thrust converges on molecular intervention paradigm in niche areas as follows:

(a)    Infection biology: (i) Study of entry and exit processes of Dengue virus from host cell which will help to understand the mechanisms of virus infection and to develop new antiviral therapies; (ii) Understand epidemiological dynamics of dengue in India

(b)   Vaccinology: (i) Development of vaccine against parasitic diseases (visceral and cutaneous leishmaniases); (ii) development of diagnostic tools against blood borne pathogens; (iii) genetic typing of pathogens.

(c)    Cancer biology: (i) Study of bacterial genetics, host-microbe dynamics and mechanisms in pathoetiogenesis of disease states like colorectal cancer, sepsis and neurological disorders related to aberrant gut microbiota; (ii) Development of microbe-based animal model and detection panels for colorectal cancer; (iii) Evaluating marketed drugs for Cancer-therapy using drug-repurposing paradigm.

(d)    Neurosciences and molecular therapeutics: (i) Design and development of neuroregenerative therapeutics using small, bacterial-derived peptides. (ii) Small molecule based metabolic supplement as an intervention strategy in neuropsychiatric disorders.

(e)    Infectious diseases:  Biology, molecular epidemiology and host pathogen interaction; new interventions including drug repurposing; point-of care lab-on-a-chip diagnostics

Collaborations

JH-IMM has successfully forged collaborations with national and international academia and research institutions as well as the government of India. Its team of high caliber and experienced scientists have secured research funding from Government of India and bi-lateral funding agencies. JH-IMM scientists have research collaborations with top of the line research and academic institutes and/or their scientists. A few of such institutes are listed below:

  • Indian Institute of Technology, Delhi
  • Central Drug Research Institute (CDRI), Lucknow, India,
  • International Centre for Genetic Engineering & Biotechnology (ICGEB), New Delhi, India
  • National Institute of Pathology (ICMR), New Delhi, India
  • National Institute of Immunology, New Delhi, India
  • University of Delhi, South/North Campus, New Delhi, India
  • Jawaharlal Nehru University, New Delhi, India
  • Amity University, Manesar, Haryana and Noida, UP, India
  • Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India
  • Translational Health Science and Technology Institute, Faridabad, UP, India
  • All India Institute of Medical Sciences, New Delhi, India
  • Food and Drug Administration, Maryland, USA
  • National Institute of Health, Maryland, USA
  • University of Colombo, Colombo, Sri Lanka
Faculty Members