ABOUT THE DEPARTMENT
The Department of Pharmaceutical Chemistry is one of the core Department, engaged in teaching and research related for development and discovery of the drugs. The Department of Pharmaceutical Chemistry at School of Pharmaceutical Education and Research (SPER), Jamia Hamdard was established in the year 1986 with M. Pharm. (Pharmaceutical Chemistry) and Ph.D. programme. The department started two-year M. Pharm. (Pharmaceutical Analysis) course in academic year 2006. The primary goal of the department is nurturing of students for advance careers in medicinal and pharmaceutical chemistry for teaching and research in academic or industrial setting. There are nine Professors, one Associate Professors and four Assistant Professors along with seven non-teaching staff.
Training in pharmaceutical chemistry a student with the ability to understand the discovery of new chemical entities for development of new drugs against epilepsy, cancer, diabetes, inflammations and infectious diseases caused tuberculosis and ESKAPE pathogens. The Department received research grants to the tune of more than Rs. 6.0 crores from various funding agencies like UGC/ICMR/ AYUSH/ AICTE/ DST/ SERB/DBT in last five years.
Vision
The Department of Pharmaceutical Chemistry aspires to be a model for educating and graduating students who are ready to compete and contribute in the ever-changing, technology-driven world of the twenty-first century.
Mission
- To provide a high-quality and innovative learning with state-of-the-art technologies which includes computer aided drug design, NMR and LC-MS/MS.
- To advance the chemical sciences through the education of graduate students by providing them with quality research and service opportunities.
- To create a learning environment where the faculty and students can discover, examine, embrace and comprehend technological changes for self-reliance.
- To embrace research that uses chemistry expertise to bridge the gap between traditional and modern medicine.
- To provide infrastructure for advance research through grants and academic collaborations
COURSES OFFERED
M. Pharm. Pharmaceutical Chemistry (4 semester programme)
M. Pharm. Pharmaceutical Analysis (4 semester programme)
Ph.D. in Pharmaceutical Chemistry
Ph.D. in Pharmaceutical Chemistry with specialization in Pharmaceutical Analysis
FACULTY MEMBERS
- Dr. Bahar Ahmad Khan, M.Sc., Ph.D., Professor & Head
- Dr. Nadeem Siddiqui, M.Pharm, Ph.D., Professor
- Dr. Mohd. Amir, M.Sc., Ph.D., Professor
- Dr. Sandhya Bawa, M.Pharm, Ph.D., Professor
- Dr. Gita Chawla, M.Pharm, Ph.D., Professor
- Dr. Asif Hussain, M.Pharm, Ph D., Professor
- Dr. Mymoona Akhtar, M. Pharm, Ph.D., Professor,
- Dr. Mohd. Shahar Yar, M. Pharm, Ph.D., Professor,
- Dr. Mohd. Mumtaz Alam, M, Pharm, Ph.D., Professor,
- Dr. Ozair Alam, M.Pharm, Ph.D., Associate Professor,
- Dr. Mohd. Shaququzzaman, M.Pharm., Ph.D., Associate Professor,
- Dr. Jamshed Haneef, Assistant Professor
- Dr. Rikeshwer Prasad Dewangan, Assistant Professor
- Dr. Md. Rafi Haider, Assistant Professor (Contractual)
INFRASTRUCTURE
No. of the classroom (including the number of working LCD projectors): 03
No. of laboratories:
UG Lab: 04
PG Lab: 02
Ph.D. Research Lab: 05
No. of seminar hall/library/reading room: 01
Instrumentations: Department has state of art instruments for characterization of synthesized molecules like TEM, LC-MS/MS, NMR, HPTLC, HPLC, FT-IR, UV-visible spectrophotometer, Elemental analyzer and other basic equipment of organic synthesis.
Thrust Area of Research
The department is well-equipped research infrastructure. Apart from wet laboratories, the department has one specialized laboratory for computer aided drug design (CADD). The thrust area of the laboratory is the designing and molecular modelling studies. We have strong research culture in the department with an emphasis on research projects, high quality of publications and Ph.D. theses.
Our department has active collaborations with the aim of interdisciplinary research to carry out the biological screening of synthesized molecules with other departments of Jamia Hamdard like HIMSR, Department of Biotechnology, SCLS, Jamia Hamdard Institute of Molecular Medicine (JHIMM). We have also active collaborations with outside national laboratories, Universities and pharmaceutical industry e.g., CSIR-IGIB, CSIR-CDRI, Jamia Milia Islamia, Amity University, BITS, AIMST Malaysia, South Asian University etc. Some of the faculty members also working on the identification and screening of phytochemicals and their structure activity relationship studies for optimization of their synthetic derivatives.
Presently, the department has 14 faculty members with wide range of research interests in the following thrust areas:
- Design and synthesis of heterocyclic drug like molecules: Design and synthesis of heterocyclic based new chemical entities e.g., pyrazolines, benzimidazoles, benzothiazoles, quinoline, cinnoline, quinazolinones, furanone, 1,4-dioxane etc and their hybrid analogues as anticonvulsants, antihypertensive, antihepatotoxic, anticancer, antitubercular agents, anti-inflammatory, antidiabetic, antibacterial and antifungals.
- Computer Aided Drug Design: Molecular docking and QSAR studies are being undertaken using the Schrodinger Software followed by bench work. We are exploring various drug target for designing of molecules e.g., PPAR gamma receptors, α-glucosidase enzyme, xanthine oxidase, EGFR Kinase, COX, MAP kinase, GABA receptor etc.
- Analytical Method Development: Development of analytical methods for drugs for pharmacokinetic and therapeutic drug monitoring purposes by using of hyphenated techniques e.g., HPLC, UPLC, LC-MS/MS and UV spectroscopy.
- Peptide Synthesis: Synthesis of peptide and peptidomimetics by using solution and solid- phase synthesis protocols. Incorporation of unnatural amino acids in the peptides of biological importance for increasing the therapeutic activity and pharmacokinetic properties of peptide drugs. We are also working on design and synthesis of self-assembling peptide-based nanomaterials and prodrugs.
- Co-crystallization of drugs: Co-crystallization is used to develop novel solid forms of existing drug molecules such as cocrystals, co-amorphous, and eutectic mixtures to enhance their biopharmaceutical properties. Besides, landscape of crystal form using experimental and computational approaches are explored to improve physicochemical and mechanical properties.
Research activities within the Department of Pharmaceutical Chemistry are well-funded by various agencies such as DST, DBT, SERB, ICMR, UGC, AICTE and CCRUM. In the last 5 years, department has received research grants worth more than Rs 6 crores from various funding agencies in India. The Department has also received two Start-up Research Grant from UGC and one early career grant from Royal Society of Chemistry. The faculty members of the department are frequent authors of top journal of national and international repute e.g., Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Bioorganic Chemistry, RSC advances etc. and published >200 papers in the last 5 years.
ACHIEVEMENTS AND AWARDS
ACTIVITIES/EVENTS
TIME TABLE
Photo-Gallery
CONTACTS US:
Prof. (Dr.) Bahar Ahmed
Head of Department,
Department of Pharmaceutical Chemistry,
School of Pharmaceutical Education and Research,
Jamia Hamdard (Deemed to be University),
New Delhi- 110062,
Email Id: bakhan_ph@jamiahamdard.ac.in
Mr. Abdus Sami Khan,
Technical Assistant,
Department of Pharmaceutical Chemistry,
School of Pharmaceutical Education and Research,
Jamia Hamdard (Deemed to be University),
New Delhi- 110062
Email Id: abdussami@jamiahamdard.ac.in